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Article

Untargeted metabolomics unveils critical metabolic signatures in novel phenotypes of acute ischemic stroke.

Metabolic brain disease - 19 Feb 2025

Jiang Yao, Wu Qian, Dang Yingqiang, Peng Lingling, Meng Ling, You Chongge

Abstract excerpt

This study aimed to identify metabolic footprints associated with distinct phenotypes of acute ischemic stroke (AIS) using untargeted metabolomics. We included 20 samples each from AIS phenotype A (n = 251), B (n = 213), and C (n = 43) groups, along with 20 age- and gender-matched healthy controls (HCs). Plasma metabolic profiles were analyzed using liquid chromatography-mass spectrometry (LC-MS). Weighted gene...

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PMID: 39969622
DOI: 10.1007/s11011-024-01451-3

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