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Intestinal Organoids: A Model to Study the Role of Microbiota in the Colonic Tumor Microenvironment

1 Nov 2020

Abstract excerpt

Colorectal cancer (CRC) is the third most common cause of cancer worldwide. Recent studies have suggested that a dysbiotic shift in the intestinal microbial composition of CRC patients influences tumorigenesis. Gut microbes are known to be integral for intestinal homeostasis; however, the mechanisms by which they impact CRC are unclear. Further knowledge about these complex interactions may guide future CRC...

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PMID: 33215543
DOI: 10.2217/fmb-2019-0345

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