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A within-host infection model to explore tolerance and resistance

13 Feb 2025

Abstract excerpt

How are some individuals surviving infections while others die? The answer lies in how infected individuals invest into controlling pathogen proliferation and mitigating damage, two strategies respectively called resistance and disease tolerance. Pathogen within-host dynamics (WHD), influenced by resistance, and its connection to host survival, determined by tolerance, decide the infection outcome. To grasp these...

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PMID: 39945508
DOI: 10.7554/elife.104052

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