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Article

Genotype and diet shape resistance and tolerance across distinct phases of bacterial infection.

BMC evolutionary biology - 22 Mar 2014

Howick Virginia M, Lazzaro Brian P

Abstract excerpt

BACKGROUND: Host defense against pathogenic infection is composed of resistance and tolerance. Resistance is the ability of the host to limit a pathogen burden, whereas tolerance is the ability to limit the deleterious effects of a given pathogen burden. This distinction recognizes that the fittest host does not necessarily have the most aggressive immune system, suggesting that host-pathogen co-evolution...

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Identifiers

PMID: 24655914
DOI: 10.1186/1471-2148-14-56
PMCID: PMC3997931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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