Article
Unprecedented female mutation bias in the aye-aye, a highly unusual lemur from Madagascar.
PLoS biology - 1 Feb 2025
Wang Richard J, Peña-García Yadira, Raveendran Muthuswamy, Harris R Alan, Nguyen Thuy-Trang, Gingras Marie-Claude, Wu Yifan, Perez Lesette, Yoder Anne D, Simmons Joe H, Rogers Jeffrey, Hahn Matthew W
Abstract excerpt
Every mammal studied to date has been found to have a male mutation bias: male parents transmit more de novo mutations to offspring than female parents, contributing increasingly more mutations with age. Although male-biased mutation has been studied for more than 75 years, its causes are still debated. One obstacle to understanding this pattern is its near universality-without variation in mutation bias, it is...
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