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NOS2 as a prognostic biomarker for early-onset colorectal cancer based on public data and clinical validation analysis

4 Feb 2025

Abstract excerpt

Early-onset colorectal cancer (EOCRC) was characterized by strong aggressiveness and high malignancy. The aim of this study was to screen suitable biomarkers for patients with EOCRC. EOCRC from The Cancer Genome Atlas Program (TCGA) database and Gene Expression Mapping (GEO) database were used to screen biomarkers for prognosis and treatment guidance. Clinical samples were used to verify the expression situation...

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PMID: 39905237
DOI: 10.1038/s41598-025-88966-6

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