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Multi-omics analysis reveals that neutrophil extracellular traps related gene TIMP1 promotes CRC progression and influences ferroptosis

31 Jan 2025

Abstract excerpt

BACKGROUND: Previous studies have found that neutrophil extracellular traps (NETs) are highly expressed in colorectal cancer (CRC) and are associated with poor prognosis. Currently, there are few studies on the relationship between NETs and CRC, so we tried to explore new markers based on NETs to assist in the treatment of CRC. METHOD: We jointly screened three major NETs genes through machine learning....

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Share to Ferroptosis and cancer prognosis
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Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms

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PMID: 39891145
DOI: 10.1186/s12935-025-03643-y

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