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Investigation of Immunoreactivity Profiles and Epitope Landscape in Divergent COVID-19 Trajectories and SARS-CoV-2 Variants.

Journal of proteome research - 7 Feb 2025

Bihani Surbhi, Ray Arka, Borishetty Dhanush, Tuckley Chaitanya, Salkar Akanksha, Acharjee Arup, Shrivastav Prithviraj, Shrivastav Om, Shastri Jayanthi, Agrawal Sachee, Duttagupta Siddhartha, Srivastava Sanjeeva

Abstract excerpt

This study aimed to elucidate the complexity of the humoral immune response in COVID-19 patients with varying disease trajectories using a SARS-CoV-2 whole proteome peptide microarray chip. The microarray, containing 5347 peptides spanning the entire SARS-CoV-2 proteome and key variants of concern, was used to analyze IgG responses in 10 severe-to-recovered, 9 nonsevere-to-severe cases, and 10 control case (5...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39873496
DOI: 10.1021/acs.jproteome.4c00791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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