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Increased fecal glycocholic acid levels correlate with obesity in conjunction with the depletion of archaea: The Dosanco Health Study

23 Jan 2025

Abstract excerpt

• A comprehensive study of 30 fecal components and their association with obesity. • Fecal glycocholic acid (GCA) and obesity showed a significant positive correlation. • Patients with high fecal GCA were depleted of an archaeal genus, methanobrevibacter . • Archaeal depletion may affect bile acid metabolism, potentially contributing to obesity. Recent studies have focused on the relationship between obesity and...

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PMID: 39863085
DOI: 10.1016/j.jnutbio.2025.109846

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