Differential effect of acute versus persistent insect-specific flavivirus infection on superinfection exclusion of West Nile, Zika and chikungunya viruses in RNAi-competent and -deficient mosquito cells

Abstract excerpt

Millions of people are annually infected by mosquito-transmitted arboviruses including dengue virus (DENV), West Nile virus (WNV), Zika virus (ZIKV) and chikungunya virus (CHIKV). Insect-specific flaviviruses (ISFs), which only infect mosquitoes and cannot replicate in vertebrates, can offer a potential one health strategy to block the transmission of arboviruses by reducing the mosquito's susceptibility for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Insect symbiosis and bacterial influences
• Share to Mosquito-borne diseases and control