Insights into the origin, hybridisation and adaptation of Candida metapsilosis hybrid pathogens.

Abstract excerpt

Hybridisation is a source of genetic diversity, can drive adaptation to new niches and has been found to be a frequent event in lineages harbouring pathogenic fungi. However, little is known about the genomic implications of hybridisation nor its impact on pathogenicity-related traits. A common limitation for addressing these questions is the narrow representativity of sequenced genomes, mostly corresponding to...

Topics

• Humans
• Candida
• Phylogeny
• Candidiasis
• Hybridization, Genetic
• Genome, Fungal
• Adaptation, Physiological