Evolutionary origin and population diversity of a cryptic hybrid pathogen.

doi:10.1038/s41467-024-52639-1

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Article

Evolutionary origin and population diversity of a cryptic hybrid pathogen.

Nature communications - 28 Sept 2024

Steenwyk Jacob L, Knowles Sonja, Bastos Rafael W, Balamurugan Charu, Rinker David, Mead Matthew E, Roberts Christopher D, Raja Huzefa A, Li Yuanning, Colabardini Ana Cristina, de Castro Patrícia Alves, Dos Reis Thaila Fernanda, Gumilang Adiyantara, Almagro-Molto María, Alanio Alexandre, Garcia-Hermoso Dea, Delbaje Endrews, Pontes Laís, Pinzan Camila Figueiredo, Schreiber Angélica Zaninelli, Canóvas David, Sanchez Luperini Rafael, Lagrou Katrien, Torrado Egídio, Rodrigues Fernando, Oberlies Nicholas H, Zhou Xiaofan, Goldman Gustavo H, Rokas Antonis

Abstract excerpt

Cryptic fungal pathogens pose disease management challenges due to their morphological resemblance to known pathogens. Here, we investigated the genomes and phenotypes of 53 globally distributed isolates of Aspergillus section Nidulantes fungi and found 30 clinical isolates-including four isolated from COVID-19 patients-were A. latus, a cryptic pathogen that originated via allodiploid hybridization. Notably, all...

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Identifiers

PMID: 39333551
DOI: 10.1038/s41467-024-52639-1
PMCID: PMC11436853

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