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Genomic exploration of the journey of Plasmodium vivax in Latin America.

PLoS pathogens - 1 Jan 2025

Lefebvre Margaux J M, Degrugillier Fanny, Arnathau Céline, Fontecha Gustavo A, Noya Oscar, Houzé Sandrine, Severini Carlo, Pradines Bruno, Berry Antoine, Trape Jean-François, Sáenz Fabian E, Prugnolle Franck, Fontaine Michael C, Rougeron Virginie

Abstract excerpt

Plasmodium vivax is the predominant malaria parasite in Latin America. Its colonization history in the region is rich and complex, and is still highly debated, especially about its origin(s). Our study employed cutting-edge population genomic techniques to analyze whole genome variation from 620 P. vivax isolates, including 107 newly sequenced samples from West Africa, Middle East, and Latin America. This...

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PMID: 39804931
DOI: 10.1371/journal.ppat.1012811
PMCID: PMC11761655

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