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Investigating the causal relationship between skin microbiota and hypertrophic scar using bidirectional mendelian randomization.

Burns : journal of the International Society for Burn Injuries - 1 Mar 2025

Hou Kai, Tan Yufang, Zhang Qi

Abstract excerpt

BACKGROUND: Hypertrophic scar (HS) is acknowledged as a pathological fibro-proliferative disease of the dermis, resulting from excessive connective tissue growth. HS significantly impacts patient quality of life due to both social and functional issues. Despite various treatments, therapeutic effectiveness remains limited, necessitating further exploration of underlying factors and mechanisms. OBJECTIVE: The...

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Acinetobacter
Genome-Wide Association Study
Mendelian Randomization Analysis
Microbiota
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39778466
DOI: 10.1016/j.burns.2025.107376

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