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Article

Reconsidering remission in recurrent late-life depression: clinical presentation and phenotypic predictors of relapse following successful antidepressant treatment.

Psychological medicine - 1 Dec 2024

Taylor Warren D, Butters Meryl A, Elson Damian, Szymkowicz Sarah M, Jennette Kyle, Baker Kiara, Renfro Brianca, Georgaras Angie, Krafty Robert, Andreescu Carmen, Ajilore Olusola

Abstract excerpt

BACKGROUND: Late-life depression (LLD) is characterized by repeated recurrent depressive episodes even with maintenance treatment. It is unclear what clinical and cognitive phenotypic characteristics present during remission predict future recurrence. METHODS: Participants (135 with remitted LLD and 69 comparison subjects across three institutions) completed baseline phenotyping, including psychiatric, medical,...

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PMID: 39773777
DOI: 10.1017/S0033291724003246
PMCID: PMC12234807

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