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Importance of EQA/PT for the detection of genetic variants in comprehensive cancer genome testing.

Scientific reports - 7 Jan 2025

Matsushita Kazuyuki, Ishige Takayuki, Watanabe Kousuke, Akahane Toshiaki, Tanimoto Akihide, Yoshimoto Michiko, Yamakuchi Munekazu, Hashiguchi Teruto, Okugawa Yoshinaga, Ikejiri Makoto, Yamaguchi Toshikazu, Yamasaki Tadashi, Takeda Mayu, Hibi Masaaki, Akiyama Naoki, Shimizu Kaho, Hashimoto Naonori, Sato Hiroko, Tanaka Yoshinori, Amari Fumie

Abstract excerpt

Comprehensive genomic profiling (CGP) is increasingly used as a clinical laboratory test and being applied to cancer treatment; however, standardization and external quality assessments (EQA) have not been fully developed. This study performed cost-effective EQA and proficiency tests (PT) for CGP testing among multiple institutions those belong to the EQA working group of Japan Association for Clinical Laboratory...

Topics

Humans
Neoplasms
Proto-Oncogene Mas
Genetic Variation
Laboratory Proficiency Testing
Genomics
Proto-Oncogene Proteins B-raf
Genetic Testing
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Cell Line, Tumor

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PMID: 39762492
DOI: 10.1038/s41598-024-84714-4

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