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DNA Methylation Associates With Sex-Specific Effects of Experimentally Increased Yolk Testosterone in Wild Nestlings.

Molecular ecology - 1 Feb 2025

Sepers Bernice, Ruuskanen Suvi, van Mastrigt Tjomme, Mateman A Christa, van Oers Kees

Abstract excerpt

Maternal hormones can profoundly impact offspring physiology and behaviour in sex-dependent ways. Yet little is known about the molecular mechanisms linking these maternal effects to offspring phenotypes. DNA methylation, an epigenetic mechanism, is suggested to facilitate maternal androgens' effects. To assess whether phenotypic changes induced by maternal androgens associate with DNA methylation changes, we...

Topics

Animals
Testosterone
DNA Methylation
Female
Egg Yolk
Male
Phenotype
Epigenesis, Genetic
Passeriformes
Sex Characteristics
Reproduction

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PMID: 39758026
DOI: 10.1111/mec.17647
PMCID: PMC11789551

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