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Article

The methylation landscape and its role in domestication and gene regulation in the chicken.

Nature ecology & evolution - 1 Dec 2020

Höglund Andrey, Henriksen Rie, Fogelholm Jesper, Churcher Allison M, Guerrero-Bosagna Carlos M, Martinez-Barrio Alvaro, Johnsson Martin, Jensen Per, Wright Dominic

Abstract excerpt

Domestication is one of the strongest examples of artificial selection and has produced some of the most extreme within-species phenotypic variation known. In the case of the chicken, it has been hypothesized that DNA methylation may play a mechanistic role in the domestication response. By inter-crossing wild-derived red junglefowl with domestic chickens, we mapped quantitative trait loci for hypothalamic...

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PMID: 32958860
DOI: 10.1038/s41559-020-01310-1
PMCID: PMC7616959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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