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Article

Prognostic value of carcinoembryonic antigen in colorectal adenocarcinoma: expanding hypotheses into clinical practice.

Clinical and experimental medicine - 3 Jan 2025

Cristaudo Adam Thomas, Morris David Lewis

Abstract excerpt

PURPOSE: This study seeks to resolve a fundamental question in oncology: Why do appendiceal and colorectal adenocarcinomas exhibit distinct liver metastasis rates? Building on our prior hypothesis published in the British Journal of Surgery, our institution has investigated potential DNA mutations within the carcinoembryonic antigen-related cell adhesion molecule (CEACAM5) gene's Pro-Glu-Leu-Pro-Lys (PELPK) motif...

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Identifiers

PMID: 39753986
DOI: 10.1007/s10238-024-01547-1
PMCID: PMC11698812

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