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Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study

3 Jan 2025

Abstract excerpt

BACKGROUND AND OBJECTIVE: Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, have emerged as promising diagnostic biomarkers for various tumours. This study aimed to identify a serum exosome ncRNA feature for enhancing GC diagnosis. DESIGNS: Serum exosomes from patients with GC (n=37) and...

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Cancer-related molecular mechanisms research
Extracellular vesicles in disease
Ferroptosis and cancer prognosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39753334
DOI: 10.1136/gutjnl-2024-333522

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