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circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX4

2 Jan 2025

Abstract excerpt

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) represents the most prevalent subtype, accounting for nearly 80% of all RCC cases. Recent research has shown that high expression of circular non-coding RNA (circRNA) is associated with poor prognosis in patients with renal clear cell carcinoma (ccRCC), however, the underlying mechanism remains unclear. METHODS: After analysing self-sequenced renal cancer and...

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PMID: 39748364
DOI: 10.1186/s12943-024-02122-8

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