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Article

CircAGAP1 promotes tumor progression by sponging miR-15-5p in clear cell renal cell carcinoma

22 Feb 2021

Abstract excerpt

BACKGROUND: Accumulating evidence has revealed that circular RNAs (circRNAs), as novel noncoding RNAs, play critical roles in carcinogenesis and tumor progression. However, the functions and molecular mechanisms of circRNAs in clear cell renal cell carcinoma (ccRCC) are largely unknown. METHODS: The expression and functions of circAGAP1 were identified in clinical samples, ccRCC cells and in vivo animal models....

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PMID: 33618745
DOI: 10.1186/s13046-021-01864-3

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