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Article

Long-term complete remission of two patients with synchronous liver metastasis from pancreatic cancer and underlying BRCA-2 mutation.

Acta gastro-enterologica Belgica - 1 Jan 2000

Crapé L, Geboes K, Kortbeek K, Naert E, Hoorens A, Berrevoet F, Van Heddeghem N, Ribeiro S

Abstract excerpt

Background: Pancreatic ductal adenocarcinoma (PDAC) has a known poor prognosis. For a select group, those with BRCA mutations, frontline platinum-based therapy and poly (ADPribose) polymerase inhibitors are options that can potentially lead to survival benefit. Patients and methods: We present 2 cases of patients with BRCAmutated pancreatic cancer with liver metastases that achieved a remarkable long-term...

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PMID: 39745039
DOI: 10.51821/87.4.11787

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