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Article

Genetic Conservation and Diversity of SARS-CoV-2 Envelope Gene Across Variants of Concern.

Journal of medical virology - 1 Jan 2025

Liu Benjamin M, Yao Qiaobin, Cruz-Cosme Ruth, Yarbrough Casey, Draper Kyah, Suslovic William, Muhammad Imaan, Contes Kaia M, Hillyard David R, Teng Shaolei, Tang Qiyi

Abstract excerpt

SARS-CoV-2 Envelope (E) protein is critical in viral assembly, release, and virulence. E gene was considered highly conserved and evolving slowly. Pan-sarbecoviruses-conserved regions in the E gene have been used as targets for various RT-PCR assays to detect SARS-CoV-2. It remains elusive whether SARS-CoV-2 variants of concern (VOCs) have accumulated significant E mutations that may affect protein stability and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39744807
DOI: 10.1002/jmv.70136
PMCID: PMC12228529

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