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Identification and validation of up-regulated TNFAIP6 in osteoarthritis with type 2 diabetes mellitus

28 Dec 2024

Abstract excerpt

Lines of evidence have indicated that type 2 diabetes mellitus (T2DM) is an independent risk factor for osteoarthritis (OA) progression. However, the study focused on the relationship between T2DM and OA at the transcriptional level remains empty. We downloaded OA- and T2DM-related bulk RNA-sequencing and single-cell RNA sequencing data from the Gene Expression Omnibus (GEO) dataset. Differential expression...

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Chemokine receptors and signaling
Inflammatory mediators and NSAID effects
Osteoarthritis Treatment and Mechanisms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39733138
DOI: 10.1038/s41598-024-82985-5

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