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Epigenomic Landscape of Human Cumulus Cells in Premature Ovarian Insufficiency Using Single‐Base Resolution Methylome and Hydroxymethylome

1 Dec 2024

Abstract excerpt

Premature ovarian insufficiency (POI) has recently been reported to be linked with epigenetic changes. Previous studies have focused on the regulation of individual genes associated with ovarian function through single-gene epigenetic variations; however, there is a deficiency in the comprehensive comprehension of the epigenetic profile for POI. Therefore, we conducted a multi-omics study integrating methylation,...

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PMID: 39706818
DOI: 10.1111/jcmm.70284

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