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Predicted breeding values for relative scrapie susceptibility for genotyped and ungenotyped sheep.

Genetics, selection, evolution : GSE - 18 Dec 2024

Eiríksson Jón H, Þórarinsdóttir Þórdís, Gautason Egill

Abstract excerpt

BACKGROUND: Scrapie is an infectious prion disease in sheep. Selective breeding for resistant genotypes of the prion protein gene (PRNP) is an effective way to prevent scrapie outbreaks. Genotyping all selection candidates in a population is expensive but existing pedigree records can help infer the probabilities of genotypes in relatives of genotyped animals. RESULTS: We used linear models to predict allele...

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Identifiers

PMID: 39695374
DOI: 10.1186/s12711-024-00947-x
PMCID: PMC11656908

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