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Article

Impact of the COL1A1 Gene Polymorphisms on Pain Perception in Tennis Elbow Patients: A Two-Year Prospective Cohort Study.

International journal of molecular sciences - 9 Dec 2024

Niemiec Paweł, Jarosz Alicja, Nowak Tomasz, Balcerzyk-Matić Anna, Iwanicki Tomasz, Iwanicka Joanna, Gawron Katarzyna, Kalita Marcin, Górczyńska-Kosiorz Sylwia, Kania Wojciech, Szyluk Karol

Abstract excerpt

The COL1A1 gene encodes the α1 chain of type I collagen, and the data reported so far demonstrate that its polymorphic variants may affect biomechanical properties of bones, muscles, and tendons, and contribute to musculoskeletal disorders. Given, however, limited research on these variants in tendon pathology, we analyzed the impact of COL1A1 polymorphisms on the tendinopathy phenotype and the effectiveness of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39684930
DOI: 10.3390/ijms252313221
PMCID: PMC11642392

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