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Molecular and Clinical Features of Adrenocortical Tumors in Beckwith–Wiedemann Spectrum

26 Nov 2024

Abstract excerpt

BACKGROUND/OBJECTIVES: Adrenocortical tumors (ACTs), including adrenocortical adenoma (ACA) and carcinoma (ACC), represent 0.3-0.4% of pediatric tumors. Beckwith-Wiedemann spectrum (BWSp) confer an increased risk of ACTs, but prognosis, management, and associated molecular characteristics are unclear. METHODS: This paper combines a literature review of 54 published cases of BWSp-ACT with a report of one newly...

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PMID: 39682154
DOI: 10.3390/cancers16233967

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