Article
Capillary leak phenotype as a major cause of death in patients with POEMS syndrome.
Leukemia - 1 Mar 2025
Lee Kenzie, Kourelis Taxiarchis, Tschautscher Marcella, Warsame Rahma, Buadi Francis, Gertz Morie, Muchtar Eli, Dingli David, Hayman Suzanne, Go Ronald, Hwa Lisa, Fonder Amie, Gonsalves Wilson, Hobbs Miriam, Kyle Robert, Kapoor Prashant, Leung Nelson, Binder Moritz, Cook Joselle, Lin Yi, Rogers Michelle, Rajkumar S Vincent, Kumar Shaji, Dispenzieri Angela
Abstract excerpt
Cause of death (COD) in POEMS (polyneuropathy, organomegaly, endocrinopathies, monoclonal protein and skin changes) syndrome is not well described. We investigated COD in patients with POEMS syndrome treated at Mayo Clinic between 2000 and 2022. Of the 89 deaths, 49 patients had known COD and were the subject of this study. Seventeen patients died of unrelated causes, while 32 patients (65%) died from causes...
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