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Article

Genotype and Associated Cancer Risk in Individuals With Telomere Biology Disorders.

JAMA network open - 2 Dec 2024

Niewisch Marena R, Kim Jung, Giri Neelam, Lunger Judith C, McReynolds Lisa J, Savage Sharon A

Abstract excerpt

Importance: Telomere biology disorders (TBDs) are inherited cancer-prone bone marrow failure syndromes with differences in morbidity and mortality based on mode of inheritance. Objective: To quantify cancer risks in TBDs by genetic subgroups. Design, Setting, and Participants: This longitudinal cohort study of TBDs assessed cancer occurrences from 2002 through 2022. Participants were individuals with a...

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Identifiers

PMID: 39661387
DOI: 10.1001/jamanetworkopen.2024.50111
PMCID: PMC11635530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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