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Article

Acute myeloid leukemia treatment outcomes with isocitrate dehydrogenase mutations: A systematic review and meta-analysis.

Medicine - 6 Dec 2024

Qin Han, Xu Rui, Yang Yingchao

Abstract excerpt

BACKGROUND: Isocitrate dehydrogenase (IDH) gene alterations and acute myeloid leukemia (AML) treatment results remain controversial. This study reviews the literature on IDH mutations in AML to determine the foundation of individualized therapy and improve effectiveness, survival time, and recurrence rate. METHODS: Seven English and 2 Chinese databases were searched for literature on IDH mutations and AML...

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Isocitrate Dehydrogenase
Leukemia, Myeloid, Acute
Mutation
Prognosis
Treatment Outcome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39654207
DOI: 10.1097/MD.0000000000040565
PMCID: PMC11630963

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