Article
Histone H4K8hib modification promotes gene expression and regulates rice immunity.
Molecular plant - 6 Jan 2025
Xu Qiutao, Ma Xuan, Wei Xuelu, Chen Zhengting, Duan Yuhang, Ju Yuliang, Wang Zhaoyun, Chen Jing, Zheng Lu, Chen Xiaolin, Huang Junbin, Zhang Jisen, Chen Xiaoyang
Abstract excerpt
This study uncovers the role of H4K8hib as an active epigenetic mark in rice that positively correlates with gene expression and enhances immune responses. Furthermore, HDA705 was identified as the key enzyme regulating H4K8hib. Mutation of HDA705 led to hyper-H4K8hib, which in turn activated the expression of defense-related genes and enhanced rice resistance to pathogens.
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