Article
A MALDI-TOF MS-based multiple detection panel of drug resistance-associated multiple single-nucleotide polymorphisms in Candida tropicalis.
Microbiology spectrum - 7 Jan 2025
Wan Feifei, Zhang Min, Guo Jian, Lin Huiping, Zhou Xiaoguang, Wang Lixin, Wu Wenjuan
Abstract excerpt
Candida tropicalis is one of the main causes of invasive candidiasis. Rapid identification of antifungal resistance is crucial for selection of an appropriate antifungal to improve patient outcomes. Mutations at specific loci are strongly correlated with resistance to antifungal agents. In this study, we developed a multi-single-nucleotide polymorphism (SNP) panel to accurately identify 36 mutation sites across...
Read the complete abstract on PubMedTopics
- Candida tropicalis
- Polymorphism, Single Nucleotide
- Antifungal Agents
- Humans
- Drug Resistance, Fungal
- Microbial Sensitivity Tests