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Correlation between rs7041 and rs4588 polymorphisms in vitamin D binding protein gene and COVID-19-related severity and mortality.

BMC medical genomics - 2 Dec 2024

Hamed Eman Riad, Abdelhady Shaymaa Abdelraheem, Al-Touny Shimaa A, Kishk Rania M, Mohamed Marwa Hussein, Rageh Fatma, Othman Amira Ahmed Abdelrahman, Abdelfatah Wagdy, Azab Hasnaa

Abstract excerpt

BACKGROUND: The vitamin D binding protein (DBP) plays a critical role in both innate and adaptive immune systems, participating in several clinical conditions, including coronavirus disease 2019 infection severity, and mortality rate. The study aimed to investigate the correlation between rs7041 and rs4588 polymorphisms in the DBP gene and Coronavirus Disease-2019 (COVID-19) severity and mortality, in patients of...

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Identifiers

PMID: 39623417
DOI: 10.1186/s12920-024-02018-y
PMCID: PMC11613538

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