Vitamin D-related polymorphisms and vitamin D levels as risk biomarkers of COVID-19 disease severity.

doi:10.1038/s41598-021-99952-z

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Vitamin D-related polymorphisms and vitamin D levels as risk biomarkers of COVID-19 disease severity.

Scientific reports - 21 Oct 2021

Freitas Ana Teresa, Calhau Conceição, Antunes Gonçalo, Araújo Beatriz, Bandeira Matilde, Barreira Sofia, Bazenga Filipa, Braz Sandra, Caldeira Daniel, Santos Susana Constantino Rosa, Faria Ana, Faria Daniel, Fraga Marta, Nogueira-Garcia Beatriz, Gonçalves Lúcia, Kovalchuk Pavlo, Lacerda Luísa, Lopes Hugo, Luís Daniel, Medeiros Fábio, Melo Ana M P, Melo-Cristino José, Miranda Ana, Pereira Clara, Pinto Ana Teresa, Pinto João, Proença Helena, Ramos Angélica, Rato João P R, Rocha Filipe, Rocha Júlio César, Moreira-Rosário André, Vazão Helena, Volovetska Yuliya, Guimarães João-Tiago, Pinto Fausto J

Abstract excerpt

Vitamin D is a fundamental regulator of host defences by activating genes related to innate and adaptive immunity. Previous research shows a correlation between the levels of vitamin D in patients infected with SARS-CoV-2 and the degree of disease severity. This work investigates the impact of the genetic background related to vitamin D pathways on COVID-19 severity. For the first time, the Portuguese population...

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PMID: 34675344
DOI: 10.1038/s41598-021-99952-z
PMCID: PMC8531279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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