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Article

Role of CD38 in mediating the effect of Bacillus on acute pancreatitis: a study of mediated Mendelian randomization.

Frontiers in immunology - 1 Jan 2024

Xiao Junhao, Tao Zhuoyan, Luo Mingjian, Yan Yong, Ke Shaobiao, Mao Benliang, Zhan Jiulin, Wang Zhe, Wang Bailin, Li Zhiwei

Abstract excerpt

Background: Some studies suggest a potential link between intestinal flora and acute pancreatitis (AP). However, the causal relationships between specific intestinal flora and AP, and the possible mediating role of immune cell traits, remain unclear. Methods: A genome-wide association study (GWAS) involving 5,959 participants was conducted to identify genetic instrumental variables associated with 473 intestinal...

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Identifiers

PMID: 39620226
DOI: 10.3389/fimmu.2024.1452743
PMCID: PMC11604618

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