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Article

WES and Transcriptome Analysis Identifies FN1 as a Candidate Gene for Anterior Segment Dysgenesis.

The journal of gene medicine - 1 Dec 2024

Lin Qinghong, Wang Xuejun, Han Xiaosong, Peng Xiaoliao, Zhang Xiaoyu, Ran Yuwen, Sun Ling, Wang Yan, Han Tian, Zhou Xingtao

Abstract excerpt

BACKGROUND: Anterior segment dysgenesis (ASD) disorders are phenotypically diverse and have multiple associated genes. This study reports on a Chinese family of three generations with ASD disorders and identifies several associated genes and pathways of the disorders. METHODS: The history of illnesses, clinical observations, and blood samples of all family members were collected. Whole exome sequencing (WES) and...

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Source

Identifiers

PMID: 39601165
DOI: 10.1002/jgm.70001

Genes

FN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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