Article
Inherited infertility: Mapping loci associated with impaired female reproduction.
American journal of human genetics - 5 Dec 2024
Ruotsalainen Sanni, Karjalainen Juha, Kurki Mitja, Lahtela Elisa, Pirinen Matti, Riikonen Juha, Ritari Jarmo, Tammi Silja, Partanen Jukka, Laivuori Hannele, Palotie Aarno, Heyne Henrike, Daly Mark, Widen Elisabeth
Abstract excerpt
Female infertility is a common and complex health problem affecting millions of women worldwide. While multiple factors can contribute to this condition, the underlying cause remains elusive in up to 15%-30% of affected individuals. In our large genome-wide association study (GWAS) of 22,849 women with infertility and 198,989 control individuals from the Finnish population cohort FinnGen, we unveil a landscape of...
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