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A prevalent caveolin-1 gene rs926198 variant is associated with type 2 diabetes mellitus in the Thai population.

Scientific reports - 11 Nov 2024

Yaikwaong Metha, Ek-Eudomsuk Pornpimon, Sittithumcharee Gunya, Anupunpisit Vipavee, Peerapatdit Thavatchai, Deerochanawong Chaicharn, Himathongkam Thep, Jirawatnotai Siwanon, Chuengsamarn Somlak

Abstract excerpt

This study investigated the associations between CAV1 variants and metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), and cardiometabolic risk factors, as well as the influence of CAV1 variants on CAV1 mRNA expression. We genotyped 743 T2DM patients for CAV1 variants. Multiple logistic regression was conducted to adjust for sex, age, and body mass index (BMI), and odds ratios (ORs) with 95% confidence...

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Identifiers

PMID: 39528503
DOI: 10.1038/s41598-024-78534-9
PMCID: PMC11555279

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