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Article

The alteration of cortical microstructure similarity in drug-resistant epilepsy correlated with mTOR pathway genes

28 Oct 2023

Abstract excerpt

BACKGROUND: Drug-resistant epilepsy (DRE) is associated with distributed laminar disruptions due to cytoarchitectonic pathologies, which may be characterized by multimodal MRI approaches such as morphometric similarity networks (MSNs). However, the genetic and histological underpinning of MSN alterations in DRE remains poorly understood, hampering its clinical application. METHODS: We enrolled 60 patients with...

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PMID: 39492369
DOI: 10.1016/j.ebiom.2023.104847

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