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Lymphocyte Antigen 6 Family Member D (LY6D) Affects Stem Cell Phenotype and Progression of Pancreatic Adenocarcinoma.

Anticancer research - 1 Nov 2024

Okimura Shumpei, Nishida Naohiro, Takahashi Hidekazu, Yokoyama Yuhki, Yamamoto Hiroyuki, Hamabe Atsushi, Ogino Takayuki, Miyoshi Norikatsu, Takahashi Hidenori, Uemura Mamoru, Kobayashi Shogo, Mori Masaki, Doki Yuichiro, Eguchi Hidetoshi, Yamamoto Hirofumi

Abstract excerpt

BACKGROUND/AIM: The membrane-bound protein lymphocyte antigen 6 family member D (LY6D), a marker of early B cell lineage is reportedly expressed in several human malignancies and has been implicated in cancer stemness. However, its expression and role in cancer stemness remain largely unexplored in pancreatic ductal adenocarcinoma (PDAC). The aim of this study was to clarify the role of LY6D in PDAC. MATERIALS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39477301
DOI: 10.21873/anticanres.17300

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