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Article

Optimization of loop mediated isothermal amplification assay (LAMP) for detection of chloroquine resistance in P. vivax malaria.

Scientific reports - 27 Oct 2024

Kaur Davinder, Kaur Upninder, Bhusal Chandra Kanta, Tak Vibhor, Sehgal Rakesh

Abstract excerpt

Chloroquine is still used as a first-line treatment for uncomplicated Plasmodium vivax malaria in India and resistance to this therapy can act as a major hurdle for malaria elimination. It is difficult to monitor drug-efficacy and drug resistance through in vivo and in vitro studies in case of Plasmodium vivax so analysis of molecular markers serves as an important tool to track resistance. Molecular methods that...

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Identifiers

PMID: 39465271
DOI: 10.1038/s41598-024-76479-7
PMCID: PMC11514184

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