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Article

Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers.

Journal of translational medicine - 24 Oct 2024

Meisinger Christa, Fischer Simone, O'Mara Tracy, Freuer Dennis

Abstract excerpt

BACKGROUND: There is evidence that inflammatory arthritis in the form of ankylosing spondylitis (AS), psoriatic arthritis (PsA), and rheumatoid arthritis are both positively and negatively associated with certain female-specific cancers. However, the study results are very heterogeneous. METHODS: Based on up to 375,814 European women, we performed an iterative two-sample Mendelian randomization to assess causal...

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Identifiers

PMID: 39449068
DOI: 10.1186/s12967-024-05765-9
PMCID: PMC11515448

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