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ALKBH5 Regulates Corneal Neovascularization by Mediating FOXM1 M6A Demethylation

23 Oct 2024

Abstract excerpt

Purpose: This study aims to explore the regulatory role and potential mechanisms of ALKBH5-mediated N6-methyladenosine (m6A) demethylation modification in corneal neovascularization (CNV). Methods: A mouse CNV model was established through corneal alkali burns. Total m6A levels were measured using an m6A RNA methylation quantification kit. The mRNA expression of candidate m6A-related enzymes was quantified by...

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PMID: 39441582
DOI: 10.1167/iovs.65.12.34

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