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Article

Working memory gating in obesity is moderated by striatal dopaminergic gene variants.

eLife - 21 Oct 2024

Herzog Nadine, Hartmann Hendrik, Janssen Lieneke Katharina, Kanyamibwa Arsene, Waltmann Maria, Kovacs Peter, Deserno Lorenz, Fallon Sean, Villringer Arno, Horstmann Annette

Abstract excerpt

Everyday life requires an adaptive balance between distraction-resistant maintenance of information and the flexibility to update this information when needed. These opposing mechanisms are proposed to be balanced through a working memory gating mechanism. Prior research indicates that obesity may elevate the risk of working memory deficits, yet the underlying mechanisms remain elusive. Dopaminergic alterations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39431987
DOI: 10.7554/eLife.93369
PMCID: PMC11493406

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