Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HNF1B Transcription Factor: Key Regulator in Renal Physiology and Pathogenesis.

International journal of molecular sciences - 2 Oct 2024

Sánchez-Cazorla Eloísa, Carrera Noa, García-González Miguel Ángel

Abstract excerpt

The HNF1B gene, located on chromosome 17q12, encodes a transcription factor essential for the development of several organs. It regulates the expression of multiple genes in renal, pancreatic, hepatic, neurological, and genitourinary tissues during prenatal and postnatal development, influencing processes such as nephrogenesis, cellular polarity, tight junction formation, cilia development, ion transport in the...

Topics

Join the communities discussing this publication.

Genetic and Kidney Cyst Diseases
Hepatocyte Nuclear Factor 1-beta
Kidney
Kidney Diseases
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pancreatic function and diabetes

Renal and related cancers

Source

Open in PubMed Open full text

Identifiers

PMID: 39408938
DOI: 10.3390/ijms251910609
PMCID: PMC11476927

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HNF1B Transcription Factor: Key Regulator in Renal Physiology and Pathogenesis.PMID 39408938Read ↗

Mechanisms of ion transport regulation by HNF1β in the kidney: beyond transcriptional regulation of channels and transportersSemantic proximity Read ↗

The Landscape of HNF1B Deficiency: A Syndrome Not Yet Fully ExploredSemantic proximity Read ↗

HNF1B-associated clinical phenotypes: the kidney and beyond.Semantic proximity Read ↗

HNF1B-associated renal and extra-renal disease-an expanding clinical spectrum.Semantic proximity Read ↗

New insights into the role of HNF-1β in kidney (patho)physiology.Semantic proximity Read ↗

From mutation to symptoms: a multi-center study on HNF1B-related nephropathy in Chinese children.Semantic proximity Read ↗

From Mutation to Symptoms: A Multi-Center Study on HNF1B-Related Nephropathy in Chinese ChildrenSemantic proximity Read ↗

[HNF1B-related disease: paradigm of a developmental gene and unexpected recognition of a new renal disease].Semantic proximity Read ↗

Criteria for HNF1B analysis in patients with congenital abnormalities of kidney and urinary tract.Semantic proximity Read ↗

Variable phenotype and genotype of pediatric patients with HNF1B nephropathy.Semantic proximity Read ↗

Autosomal dominant tubulointerstitial kidney disease: more than just HNF1β.Semantic proximity Read ↗

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.