Article
Direct Klebsiella pneumoniae Carbapenem Resistance and Carbapenemases Genotype Prediction by Al-MOF/TiO2@Au Cubic Heterostructures-Assisted Intact Bacterial Cells Metabolic Analysis.
Analytical chemistry - 29 Oct 2024
Ma Dumei, Wang Yongqi, Ye Jiacheng, Ding Chuan-Fan, Yan Yinghua
Abstract excerpt
Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections pose a significant threat to human health. Fast and accurate prediction of K. pneumoniae carbapenem resistance and carbapenemase genotype is critical for guiding antibiotic treatment and reducing mortality rates. In this study, we prese...
Topics
- Klebsiella pneumoniae
- Titanium
- beta-Lactamases
- Bacterial Proteins
- Metal-Organic Frameworks
- Gold
- Genotype
- Anti-Bacterial Agents
- Humans
- Carbapenems
- Microbial Sensitivity Tests
- Drug Resistance, Bacterial