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Rapid evolution leads to extensive genetic diversification of cattle flu Influenza D virus.

Communications biology - 7 Oct 2024

Limaye Sanket, Lohar Tejas, Dube Harita, Ramasamy Santhamani, Kale Mohan, Kulkarni-Kale Urmila, Kuchipudi Suresh V

Abstract excerpt

Influenza D virus (IDV), the cattle flu virus, is a novel multi-host RNA virus, circulating silently worldwide, with widespread seropositivity among US cattle, reaching up to 80% in some areas raising a potential threat of cattle-to-human transmission. Currently, five genetic lineages of IDV have been described, but their evolutionary dynamics have not been studied. Although IDV was first identified in 2011, our...

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Identifiers

PMID: 39375524
DOI: 10.1038/s42003-024-06954-4
PMCID: PMC11458855

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