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Human pegivirus -1 (HPgV-1) RNA frequency and genotype distribution in pediatric oncology patients with febrile neutropenia.

Virus research - 1 Dec 2024

da Silva Anielly Sarana, de Campos Gabriel Montenegro, Altizani Gabriela Marengone, Barros Alice Chagas, Junqueira Dennis Maletich, Kashima Simone, Sampaio Sandra Coccuzzo, Elias Maria Carolina, Giovanetti Marta, Scrideli Carlos Alberto, Slavov Svetoslav Nanev

Abstract excerpt

Human Pegivirus-1, typically regarded as a commensal virus, exhibits high prevalence in humans. Its frequency and impact on oncologic pediatric patients with febrile neutropenia (FN), a frequent chemotherapy complication, remains unexplored. In this study, we assessed HPgV-1 RNA prevalence in pediatric patients experiencing FN. Blood samples were collected from 30 children, 15 presenting FN and 15 comprising a...

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PMID: 39374843
DOI: 10.1016/j.virusres.2024.199479

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